Selected Publications

Selected Publications – Harel Lab

  • Solomon O, Patriat R, Braun H, Palnitkar T, Moeller S, Auerbach E, Ugurbil K, Sapiro S & Harel N (2023). Motion Robust Magnetic Resonance Imaging Via Efficient Fourier Aggregation. Med Image Anal. 2023 Jan;83:102638. doi: 10.1016/j.media.2022.102638. Epub 2022 Sep 26.

  • Vitek JL, Patriat R, Ingham L, Reich MM, Volkmann J & Harel N. (2022) Lead Location as a Determinant of Motor Benefit in Subthalamic Nucleus Deep Brain Stimulation for Parkinson’s Disease. Front Neurosci. 2022 Oct 4;16:1010253. doi: 10.3389/fnins.2022.1010253. eCollection 2022. PMID: 36267235.

  • Patriat R, Pisharady PK, Amundsen-Huffmaster S, Linn-Evans M, Howell M, Chung JW, Petrucci MN, Videnovic A, Holker E, De Kam J, Tuite P, Lenglet C, Harel N, MacKinnon CD. (2022) White matter microstructure in Parkinson's disease with and without elevated rapid eye movement sleep muscle tone. Brain Commun. 2022 Feb 9;4(2):fcac027. doi: 10.1093/braincomms/fcac027. eCollection 2022. PMID: 35310831.

  • Solomon O, Palnitkar T, Patriat R, Braun H, Aman J, Park MC, Vitek J, Sapiro G & Harel N. (2021) Deep-learning based fully automatic segmentation of the globus pallidus interna and externa using ultra-high 7 Tesla MRI. Hum Brain Mapp. 2021 Jun 15;42(9):2862-2879. doi: 10.1002/hbm.25409. Epub 2021 Mar 18. PMID: 33738898.

  • Schrock LE, Patriat R, Goftari M, Kim J, Johnson MD, Harel N & Vitek JL. (2021) 7T MRI and Computational Modeling Supports a Critical Role of Lead Location in Determining Outcomes for Deep Brain Stimulation: A Case Report. Front Hum Neurosci. 2021 Feb 11;15:631778. doi: 10.3389/fnhum.2021.631778. eCollection 2021. PMID: 33679351.

  • Niederer J, Patriat R, Rosenberg O, Palnitkar T, Park MC, Darrow D, Schrock L, Eberly LE & Harel N. (2020) Factors Influencing Electrode Position and Bending of the Proximal Lead in Deep Brain Stimulation for Movement Disorders. (2020) Stereotact Funct Neurosurg. 2020 Jun 2:1-13. doi: 10.1159/000507029. PMID: 32485728.

  • Kim J, Patriat R, Kaplan J, Solomon O & Harel N. (2020) Deep Cerebellar Nuclei Segmentation via Semi-Supervised Deep Context-Aware Learning from 7T Diffusion MRI. IEEE Access. 2020; 8:101550-101568. doi: 10.1109/access.2020.2998537. Epub 2020 May 29. PMID: 32656051.

  • Patriat R, Kaplan J, Niederer J, Huffmaster S, Petrucci M, Harel N & MacKinnon C. (2020) Morphological changes in the subthalamic nucleus of people with mild-to-moderate Parkinson’s disease: a 7T MRI study. Sci Rep. 2020 May 29;10(1):8785. doi: 10.1038/s41598-020-65752-0. PMID: 32472044.

  • Duchin Y, Shamir R, Patriat R, Kim J, Vitek J, Sapiro G & Harel N.  (2018) Patient-specific anatomical model for deep brain stimulation based on 7 Tesla MRI. PLoS ONE 2018 Aug 22;13(8):e0201469.

  • Patriat R, Cooper S, Duchin Y, Niederer J, Lenglet C, Aman J, Park MC, Vitek J, & Harel N. (2018) Individualized Tractography-Based Parcellation of the Globus Pallidus Pars Interna using 7T MRI in Movement Disorder Patients Prior to DBS Surgery. Neuroimage. 2018 Sep;178:198-209. doi: 10.1016/j.neuroimage.2018.05.048. Epub 2018 May 19. PMID: 29787868.

  • Shamir R, Duchin Y, Kim J, Patriat R, Marmor O, Bergman H, Vitek JL, Sapiro G, Bick A, Eliyahu R, Eitan R, Israel Z & Harel N. (2018) Microelectrode recordings validate the clinical visualization of subthalamic-nucleus based on 7T MRI and machine-learning for deep brain stimulation surgery. Neurosurgery. 2019 Mar 1;84(3):749-757. doi: 10.1093/neuros/nyy212. PMID: 29800386.

  • Eryaman Y, Kobayashi N, Moen S, Aman J, Grant A, Vaughan J.T, Molnar G, Park M.C, Vitek J, Adriany G, Ugurbil K & Harel N. (2018) A simple geometric analysis method for measuring and mitigating RF induced currents on Deep Brain Stimulations leads by multichannel transmission/reception. NeuroImage. 2018 Sep 28;184:658-668.

  • Kim J, Duchin Y, Shamir R, Patriat R, Vitek J, Harel N & Sapiro. (2018) Automatic Localization of the Subthalamic Nucleus on Patient-Specific Clinical MRI by Incorporating 7T MRI and Machine Learning: Application in Deep Brain Stimulation. Hum Brain Mapp. 2018;1–20. https://doi.org/10.1002/hbm.24404.

  • Plantinga B, Temel Y, Duchin Y, Uludag K, Patriat R, Roebroeck A, Kuijf M, Jahanshahi A, ter Haar Romenij B, Vitek JL & Harel N. (2016) Individualized parcellation of the subthalamic nucleus in patients with Parkinson's disease with 7T MRI. Neuroimage. 2018 Mar:168:403-411. doi: 10.1016/j.neuroimage.2016.09.023. Epub 2016 Sep 26.

  • Kim J, Lenglet C, Duchin Y, Sapiro G and Harel N. (2014) Semi-automatic Segmentation of Brain Subcortical Structures from High-field MRI. IEEE J Biomed Health Inform Vol. 18 No 5, Sept. 2014 (TITB-00488-2013).

  • Duchin Y, Abosch A, Yacoub E, Sapiro G & Harel N. (2012) Feasibility of using ultra-high field (7T) MRI for clinical surgical targeting. PLoS One. 2012;7(5):e37328. Epub 2012 May 17.

  • Harel N. (2012) Ultra high-resolution fMRI at ultra-high field. NeuroImage 2012 Aug 15;62(2):1024-8.

  • Lenglet C, Abosch A, Yacoub E, De Martino F, Sapiro S & Harel N. (2012) Comprehensive in vivo Mapping of the Human Basal Ganglia and Thalamic Connectome in Individuals using 7T MRI. PLoS ONE 2012 7(1): e29153. doi:10.1371.

  • Abosch A, Yacoub E, Ugurbil K & Harel N. (2010). An Assessment of Current Brain Targets for Deep Brain Stimulation Surgery using Susceptibility-Weighted Imaging at 7T. Neurosurgery 2010 Dec;67(6):1745-56; discussion 1756.

  • Yacoub E, Harel N & Uğurbil K. (2008) High field fMRI Unveils Orientation Columns in Humans. Proc Natl Acad Sci U S A. 2008 Jul 29;105(30):10607-12.

  • Harel N, Lin J, Moeller S, Ugurbil K & Yacoub E. (2006) Combined imaging-histological study of cortical laminar specificity of fMRI signals. NeuroImage 29(3):879-87.

  • Bolan PJ, Yacoub E, Garwood M, Ugurbil K & Harel N. (2006) In Vivo Micro-MRI of Intracortical Neurovasculature. NeuroImage 32(1):62-9. – Cover.

 

 

Selected Publications – with collaborators

  • Sadeghi-Tarakameh A, DelaBarre L, Zulkarnain NIH, Harel N, Eryaman Y (2023). Implant-friendly MRI of deep brain stimulation electrodes at 7T. Magn Reson Med. 2023 Aug 2. doi: 10.1002/mrm.29825. PMID: 37533196.

  • Hill ME, Johnson LA, Wang J, Escobar Sanabria D, Patriat R, Cooper SE, Park MC, Harel N, Vitek JL, Aman JE. (2023) Paradoxical Modulation of STN β-Band Activity with Medication Compared to Deep Brain Stimulation. Mov Disord. 2023 Oct 27. doi: 10.1002/mds.29634. Online ahead of print. PMID: 37888906

  • Sadeghi-Tarakameh A, Zulkarnain NIH, He X, Atalar E, Harel N, Eryaman Y. A workflow for predicting temperature increase at the electrical contacts of deep brain stimulation electrodes undergoing MRI (2022). Magn Reson Med. 2022; Nov;88(5):2311-2325. doi: 10.1002/mrm.29375. Epub 2022 Jul 4. PMID: 35781696.

  • Johnson L, Aman J, Yu Y, Sanabria D, Wang J, Hill M, Dharnipragada R, Patriat R, Fiecas M, Li L, Schrock L, Cooper S, Johnson M, Park M, Harel N & Vitek J. (2021) High-Frequency Oscillations in the Pallidum: A Pathophysiological Biomarker in Parkinson's Disease? Mov Disord. 2021 Jun;36(6):1332-1341. doi: 10.1002/mds.28566. Epub 2021 Apr 13. PMID: 33847406.

  • Griera MD, Yacoubb E, Adriany G,Lagore R, Harel N, Zhangf R, Lenglet C, Uğurbil K, Zimmermanna J, Heilbronner SR (2022) Ultra-high field (10.5T) diffusion-weighted MRI of the macaque brain. NeuroImage. 2022 Apr 13;255:119200. doi: 10.1016/j.neuroimage.2022.119200. PMID: 35427769.

  • Yacoub E, Grier MD, Auerbach EJ, Lagore RL, Harel N, Ugurbil K, Adriany G, Zilverstand A, Hayden BY, Heilbronner SR & Zimmermann J. (2020) Ultra-high field (10.5 T) resting state fMRI in the macaque. NeuroImage 2020 Sep 5:117349. doi: 10.1016/j.neuroimage.2020.117349. Online ahead of print. PMID: 32898683

  • Aman JE, Johnson LA, Sanabria DE, Wang J, Patriat R, Hill M, Marshall E, MacKinnon CD, Cooper SE, Schrock LE, Park MC, Harel N, Vitek JL. (2020) Directional deep brain stimulation leads reveal spatially distinct oscillatory activity in the globus pallidus internus of Parkinson's disease patients. Neurobiol Dis. 2020 Jun;139:104819. doi: 10.1016/j.nbd.2020.104819. Epub 2020 Feb 20. PMID: 32088379.

  • Gunalan K, Chaturvedi A, Howell B, Duchin Y, Lempka S, Patriat R, Sapiro G, Harel N & McIntyre C. (2017) Creating and parameterizing patient-specific deep brain stimulation pathway-activation models using the hyperdirect pathway as an example. PLoS One. 2017 Apr 25;12(4):e0176132.

  • Van Essen DC, Ugurbil K, Auerbach E, Barch D, Behrens TE, Bucholz R, Chang A, Chen L, Corbetta M, Curtiss SW, Della Penna S, Feinberg D, Glasser MF, Harel N, Heath AC, Larson-Prior L, Marcus D, Michalareas G, Moeller S, Oostenveld R, Petersen SE, Prior F, Schlaggar BL, Smith SM, Snyder AZ, Xu J, Yacoub E; WU-Minn HCP Consortium. The Human Connectome Project: A data acquisition perspective (2012). NeuroImage 2012 Feb 17.

  • Harel N, Lee S-L, Kim D-S, Nagaoka T & Kim S-G. (2002) Origin of Negative Blood Oxygenation Level–Dependent fMRI Signals. J Cereb Blood Flow and Metab  22:908-917.

  • Harrison RV, Harel N, Panesar J, Mount RJ. (2002) Blood capillary distribution correlates with hemodynamic based functional imaging in cerebral cortex. Cereb Cortex 12: 225-233 - Cover.